Cane Lukisari*, Dwi Setyaningtyas*, Nafi’ah*, Maharani Laillyza Apriasari**

*Oral Medicine Department, Faculty of Dentistry, Universitas Hang Tuah and Dr. Ramelan Naval Hospital,Surabaya, Indonesia
**Oral Medicine Department, Faculty of Dentistry, Universitas Lambung Mangkurat, Banjarmasin, Indonesia

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Primary herpetic gingivostomatitis (PHGS) is the most common manifestation of herpes simplex virus type 1 (HSV-1) infection with characteristics of oral and/or perioral vesicular ulcerative lesions, inflamed gingival margins, and characteristic prodromal symptoms. This disease is common in children. It is a self-limiting disease laboratory tests to confirm the diagnosis. Treatments include causative, symptomatic, and supportive therapies. The choice of treatment for causative agent elimination used in this case was acyclovir.

Case Report
This paper reported and discussed a case of PHGS diagnosed based on the patient's anamnesis and typical clinical pictures. It was in the form of ulcerated lesions on the oral and perioral mucosa and generalized inflammation of the gingiva. Treatment result was the patient recovered with routine Acyclovir therapy, Benzidamine HCl mouthwash, antipyretic and supportive therapy i.e multivitamins, hydration, liquid diet of High Calories High Protein (HCHP) and adequate rest. Patient was then followed up closely each third days to record the diseases’ progress. Although antiviral acyclovir was only indicated for immunocompromised children, in this case it helps patient to prevent further exacerbation and shortening the duration of illness.

PHGS therapy includescausative, symptomatic and supportive therapy. Administration of the antiviral drug acyclovir was still effectiveand if the patient arrives after the 72-hour phase acyclovir is still needed to prevent further spread of the virus. Key words: primary herpetic gingivostomatitis, therapeutic approach, acyclovir, aloe vera

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